PMID: 8820951

Fine RL, Chambers TC, Sachs CW
P-glycoprotein, multidrug resistance and protein kinase C.
Stem Cells. 1996 Jan;14(1):47-55., [PubMed]
Sentences
No. Mutations Sentence Comment
97 ABCB1 p.Ser671Asn
X
ABCB1 p.Ser671Asn 8820951:97:12
status: NEW
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 Mutation of serine 671 to asparagine in the linker region of P-glycoprotein abrogated verapamil and PKC-α-stimulated ATPase activity. Login to comment 142 ABCB1 p.Gly185Val
X
ABCB1 p.Gly185Val 8820951:142:61
status: NEW
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 The human MDR1 P-glycoprotein, with a mutation of amino acid glycine 185 to valine, was also expressed in Sf9 cells and used as membrane vesicles. Login to comment