PMID: 7568044

Volkman SK, Cowman AF, Wirth DF
Functional complementation of the ste6 gene of Saccharomyces cerevisiae with the pfmdr1 gene of Plasmodium falciparum.
Proc Natl Acad Sci U S A. 1995 Sep 12;92(19):8921-5., 1995-09-12 [PubMed]
Sentences
No. Mutations Sentence Comment
38 ABCB4 p.Asn1042Asp
X
ABCB4 p.Asn1042Asp 7568044:38:200
status: NEW
view ABCB4 p.Asn1042Asp details
 Shuttle plasmids constructed with the pYES-2 vector (Invitrogen) contained either the wild-typepfindrl gene (pYpfmdrl) or a mutantpfindrl gene with a serine to cysteine change at position 1034 and an asparagine to aspartic acid change at position 1042 (pYpfmdrlCD) (2). Login to comment 130 ABCB1 p.Gly185Val
X
ABCB1 p.Gly185Val 7568044:130:127
status: NEW
view ABCB1 p.Gly185Val details
 One possible explanation for these results (19) is the presence of a mutation in the MDR1 gene which resulted in a change from glycine to valine at amino acid position 185. Login to comment