PMID: 7515441

Cuthbert A
Cystic fibrosis gene update.
J R Soc Med. 1994;87 Suppl 21:2-4., [PubMed]
Sentences
No. Mutations Sentence Comment
14 ABCC7 p.Lys335Glu
X
ABCC7 p.Lys335Glu 7515441:14:69
status: NEW
view ABCC7 p.Lys335Glu details
 (c) Directed mutagenesis (ie conversion oflysine 95 to aspartate and lysine 335 to glutamate) altered the ion selectivity of CFTR chloride channels from Br>Cl->I->Fto I->Br->Cl->F-6. Login to comment