PMID: 7508188

Gray MA, Winpenny JP, Porteous DJ, Dorin JR, Argent BE
CFTR and calcium-activated chloride currents in pancreatic duct cells of a transgenic CF mouse.
Am J Physiol. 1994 Jan;266(1 Pt 1):C213-21., [PubMed]
Sentences
No. Mutations Sentence Comment
191 ABCC7 p.Arg334Trp
X
ABCC7 p.Arg334Trp 7508188:191:112
status: NEW
view ABCC7 p.Arg334Trp details
ABCC7 p.Arg347Pro
X
ABCC7 p.Arg347Pro 7508188:191:123
status: NEW
view ABCC7 p.Arg347Pro details
 Interestingly, CFTR containing missense mutations that are associated with pancreatic sufficiency (e.g., Rll7H, R334W, and R347P, see Ref. 24) can generate 530% of the wild-type chloride current density in transfected cells (31). Login to comment