PMID: 26289599

Jansson K, Venugopal J, Sanchez G, Magenheimer BS, Reif GA, Wallace DP, Calvet JP, Blanco G
Ouabain Regulates CFTR-Mediated Anion Secretion and Na,K-ATPase Transport in ADPKD Cells.
J Membr Biol. 2015 Dec;248(6):1145-57. doi: 10.1007/s00232-015-9832-7. Epub 2015 Aug 20., [PubMed]
Sentences
No. Mutations Sentence Comment
35 ABCC7 p.Ser489*
X
ABCC7 p.Ser489* 26289599:35:11
status: NEW
view ABCC7 p.Ser489* details
 Cftrm1UNC (S489X) mice, which exhibit a null CFTR phenotype due to unstable CFTR expression at the mRNA and protein level (Takacs-Jarrett et al. 2001), were also used in this study. Login to comment