ABCMdb

PMID: 25960213

Subhani S, Jayaraman A, Jamil K
Homology modelling and molecular docking of MDR1 with chemotherapeutic agents in non-small cell lung cancer.
Biomed Pharmacother. 2015 Apr;71:37-45. doi: 10.1016/j.biopha.2015.02.009. Epub 2015 Feb 19., [PubMed]

Sentences

No. Mutations Sentence Comment

42 ABCB1 p.Val34Ala The amino acids from Val 34 to Ala 1275 of Human MDR1 were only used for modelling since the corresponding template co-ordinates are available only for this region. Login to comment 43 ABCB1 p.Ala631Leu Further, the residues corresponding to Ala 631-Leu 688 were also not included for modelling as there is a break in the template structure as well in the region corresponding to these residues. Login to comment 109 ABCB1 p.Val34Ala Residues from Val 34-Ala 1275 were used for modelling. Login to comment 110 ABCB1 p.Ala631Leu The residues Ala 631-Leu 688 which were not used for modelling have been highlighted. Login to comment