PMID: 25901298

Golabek K, Strzelczyk JK, Owczarek A, Cuber P, Slemp-Migiel A, Wiczkowski A
Selected mechanisms of molecular resistance of Candida albicans to azole drugs.
Acta Biochim Pol. 2015;62(2):247-51. doi: 10.18388/abp.2014_940. Epub 2015 Apr 21., [PubMed]
Sentences
No. Mutations Sentence Comment
90 ABCB1 p.Thr1203Cys
X
ABCB1 p.Thr1203Cys 25901298:90:244
status: NEW
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ABCB1 p.Ala354Gly
X
ABCB1 p.Ala354Gly 25901298:90:158
status: NEW
view ABCB1 p.Ala354Gly details
 Sequence analysis of the ERG11 gene in the studied Candida albicans strains revealed 19 different mutations: T462C, T495A, A504G, A530C, C558T, G622A, C216T, A354G, A1587G, T1617C, G1309A, T1143C, A1167G, A1173G, A1230G, C1257T, T1287C, A945C, T1203C. Login to comment 92 ABCB1 p.Ala354Gly
X
ABCB1 p.Ala354Gly 25901298:92:20
status: NEW
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 Mutations C558T and A354G were common only in azole-sensitive strains of Candida albicans. Login to comment