PMID: 2573836

Azzaria M, Schurr E, Gros P
Discrete mutations introduced in the predicted nucleotide-binding sites of the mdr1 gene abolish its ability to confer multidrug resistance.
Mol Cell Biol. 1989 Dec;9(12):5289-97., [PubMed]
Sentences
No. Mutations Sentence Comment
410 ABCB1 p.Lys48Arg
X
ABCB1 p.Lys48Arg 2573836:410:12
status: NEW
view ABCB1 p.Lys48Arg details
 Mutation of lysine48 to arginine in the yeast RAD3 protein abolishes its ATPase and DNA helicase activities but not the ability to bind ATP. Login to comment