PMID: 25563194

Zhu DQ, Zou Q, Hu CH, Su JL, Zhou GH, Liu P
XRCC1 genetic polymorphism acts a potential biomarker for lung cancer.
Tumour Biol. 2015 May;36(5):3745-50. doi: 10.1007/s13277-014-3014-6. Epub 2015 Jan 8., [PubMed]
Sentences
No. Mutations Sentence Comment
44 ABCB1 p.Thr522Ser
X
ABCB1 p.Thr522Ser 25563194:44:415
status: NEW
view ABCB1 p.Thr522Ser details
 We found that all of these genetic variants were non-synonymous mutations, C > T, rs1799782 in exon6 of XRCC1 resulting in a arginine (Arg) to tryptophan (Trp) acid replacement (p. Arg 194 Trp), G > A, rs25487 in exon10 of XRCC1 resulting in a arginine (Arg) to glutamine (Gln) acid replacement (p. Arg 399 Gln), c.1564A > T in exon15 of MDR1 resulting in threonine (Thr) to serine (Ser) amino acid replacement (p. Thr 522 Ser) and c.3073A > C in exon22 of MDR1 resulting in a leucine (Leu) to phenylalanine (Phe) acid replacement (p.Leu 860 Phe). Login to comment