PMID: 25300953

Niesor EJ, Chaput E, Mary JL, Staempfli A, Topp A, Stauffer A, Wang H, Durrwell A
Effect of compounds affecting ABCA1 expression and CETP activity on the HDL pathway involved in intestinal absorption of lutein and zeaxanthin.
Lipids. 2014 Dec;49(12):1233-43. doi: 10.1007/s11745-014-3958-8. Epub 2014 Oct 10., [PubMed]
Sentences
No. Mutations Sentence Comment
17 ABCA1 p.Glu89Lys
X
ABCA1 p.Glu89Lys 25300953:17:52
status: NEW
view ABCA1 p.Glu89Lys details
 In the Wisconsin HypoAlpha Mutant chicken, a single E89K loss of function mutation in the ATP-binding cassette transporter (ABC) A1 gene [12] results in a [95 % decrease in HDL cholesterol (HDL-C) [13], and dietary supplementation with lutein is poorly effective in raising plasma, tissue, and retinal lutein [14]. Login to comment