PMID: 24974227

Carlile GW, Robert R, Goepp J, Matthes E, Liao J, Kus B, Macknight SD, Rotin D, Hanrahan JW, Thomas DY
Ibuprofen rescues mutant cystic fibrosis transmembrane conductance regulator trafficking.
J Cyst Fibros. 2015 Jan;14(1):16-25. doi: 10.1016/j.jcf.2014.06.001. Epub 2014 Jun 25., [PubMed]
Sentences
No. Mutations Sentence Comment
44 ABCC8 p.Ala116Pro
X
ABCC8 p.Ala116Pro 24974227:44:185
status: NEW
view ABCC8 p.Ala116Pro details
 HEK cells stably expressing HA-tagged hERG G601S or wild-type hERG were given by Eckhard Ficker (Case Western Reserve University U.S.A.) Flag-tagged hamster SUR1 both the wild-type and A116P mutant form and rat Kir6.2 plasmids were given by Show-Ling Shyng (Oregon Health and Science University) and were reported previously [18]. Login to comment 158 ABCC8 p.Ala116Pro
X
ABCC8 p.Ala116Pro 24974227:158:61
status: NEW
view ABCC8 p.Ala116Pro details
 Persistent hyperinsulinemic hypoglycemia of infancy mutation A116P in the sulfonylurea receptor 1 (SUR1) expressed in HeLa cells was treated (24 h) with ibuprofen. Login to comment