PMID: 24624364

Sharom FJ
Complex Interplay between the P-Glycoprotein Multidrug Efflux Pump and the Membrane: Its Role in Modulating Protein Function.
Front Oncol. 2014 Mar 3;4:41. doi: 10.3389/fonc.2014.00041. eCollection 2014., [PubMed]
Sentences
No. Mutations Sentence Comment
169 ABCB1 p.Phe335Ala
X
ABCB1 p.Phe335Ala 24624364:169:143
status: NEW
view ABCB1 p.Phe335Ala details
This structure is compatible with decades of biochemical analysis on the human protein, and helps to explain perplexing functional data on the Phe335Ala mutant. Login to comment