PMID: 24609033

Young JC
The role of the cytosolic HSP70 chaperone system in diseases caused by misfolding and aberrant trafficking of ion channels.
Dis Model Mech. 2014 Mar;7(3):319-29. doi: 10.1242/dmm.014001., [PubMed]
Sentences
No. Mutations Sentence Comment
141 ABCC7 p.Val510Asp
X
ABCC7 p.Val510Asp 24609033:141:105
status: NEW
view ABCC7 p.Val510Asp details
 However, ƊF508 CFTR trafficking was improved by DNAJB12 knockdown combined with another stabilizing V510D mutation within CFTR and a small-molecule stabilizer, Corrector-4 (Grove et al., 2011). Login to comment