PMID: 24321342

Zhang Y, Hu Y, Feng Y, Kodithuwakku ND, Fang W, Li Y, Huang W
The inhibitory and combinative mechanism of HZ08 with P-glycoprotein expressed on the membrane of Caco-2 cell line.
Toxicol Appl Pharmacol. 2014 Jan 15;274(2):232-9. doi: 10.1016/j.taap.2013.11.019. Epub 2013 Dec 7., [PubMed]
Sentences
No. Mutations Sentence Comment
251 ABCB1 p.Ser222Cys
X
ABCB1 p.Ser222Cys 24321342:251:77
status: NEW
view ABCB1 p.Ser222Cys details
 In another research of Tip W. Loo, verapamil significantly protects residues S222C (TM4), L339 (TM6), A342 (TM6), and G984 (TM12) from inactivation by MTS-verapamil. Login to comment