ABCMdb

PMID: 23996049

Abdul Wahab A, Taj-Aldeen SJ, Hagen F, Diophode S, Saadoon A, Meis JF, Klaassen CH
Genotypic diversity of Pseudomonas aeruginosa in cystic fibrosis siblings in Qatar using AFLP fingerprinting.
Eur J Clin Microbiol Infect Dis. 2014 Feb;33(2):265-71. doi: 10.1007/s10096-013-1954-1. Epub 2013 Sep 1., [PubMed]

Sentences

No. Mutations Sentence Comment

3 ABCC7 p.Ile1234Val This work reports the genotypic relatedness of P. aeruginosa in CF patients with the CFTR I1234V mutation, and to determine whether the genotypes are identical among CF siblings and among different families with the same CFTR mutation. Login to comment 22 ABCC7 p.Ile1234Val The CFTR I1234V mutation is one of the common mutations among Arabs in the Gulf region belonging to a large kindred Arab tribe [13, 14]. Login to comment 23 ABCC7 p.Ile1234Val The prevalence of P. aeruginosa in lower respiratory cultures of CF patients with CFTR I1234V mutation was 60.9 % [15]. Login to comment 27 ABCC7 p.Ile1234Val Materials and methods Patients and sampling Between March 2010 and June 2011, sputum samples or deep pharyngeal swabs were prospectively collected and cultured from CF patients with the CFTR I1234V mutation attending the CF clinic at Hamad Medical Corporation, Doha, Qatar. Login to comment 42 ABCC7 p.Ile1234Val Twelve families (F1-12 constitute 22 CF patients with CFTR I1234V mutation (denoted as "A" in Table 1) belong to a single large Arab kindred tribe with positive P. aeruginosa culture. Login to comment