PMID: 23977375

Kim S, Beyer BA, Lewis C, Nadel JA
Normal CFTR inhibits epidermal growth factor receptor-dependent pro-inflammatory chemokine production in human airway epithelial cells.
PLoS One. 2013 Aug 16;8(8):e72981. doi: 10.1371/journal.pone.0072981. eCollection 2013., [PubMed]
Sentences
No. Mutations Sentence Comment
56 ABCC7 p.Trp1282*
X
ABCC7 p.Trp1282* 23977375:56:152
status: NEW
view ABCC7 p.Trp1282* details
 Cells containing mutant CFTR versus isogenic cells corrected with wild-type CFTR: Human airway epithelial (IB3) cells expressing mutant CFTR (deltaF508/W1282X; [33]) and isogenic airway epithelial (C38) cells complemented with wild-type CFTR [34] were purchased from American Type Culture Collection, and were grown in LHC-8 medium (Invitrogen, Grand Island, NY) containing 5% fetal bovine serum, penicillin (100 U/ml), and streptomycin (100 mcg/ml) at 37uC in a humidified 5% CO2 water-jacketed incubator. Login to comment