PMID: 23901103

Ward AB, Szewczyk P, Grimard V, Lee CW, Martinez L, Doshi R, Caya A, Villaluz M, Pardon E, Cregger C, Swartz DJ, Falson PG, Urbatsch IL, Govaerts C, Steyaert J, Chang G
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13386-91. doi: 10.1073/pnas.1309275110. Epub 2013 Jul 30., [PubMed]
Sentences
No. Mutations Sentence Comment
62 ABCB10 p.Ser80Cys
X
ABCB10 p.Ser80Cys 23901103:62:32
status: NEW
view ABCB10 p.Ser80Cys details
ABCB10 p.Ser305Cys
X
ABCB10 p.Ser305Cys 23901103:62:94
status: NEW
view ABCB10 p.Ser305Cys details
These mutants included residues S80C, S176C, M188C, A216C, S218C, A250C, R272C, L283C, G284C, S305C, A309C, G342C, A344C, K730C, S876C, S889C, and S975C distributed throughout the TM helices. Login to comment