PMID: 23788109

Koldehoff M, Zakrzewski JL, Beelen DW, Elmaagacli AH
Additive antileukemia effects by GFI1B- and BCR-ABL-specific siRNA in advanced phase chronic myeloid leukemic cells.
Cancer Gene Ther. 2013 Jul;20(7):421-7. doi: 10.1038/cgt.2013.31. Epub 2013 Jun 21., [PubMed]
Sentences
No. Mutations Sentence Comment
92 ABCB1 p.Glu255Lys
X
ABCB1 p.Glu255Lys 23788109:92:301
status: NEW
view ABCB1 p.Glu255Lys details
 Additive effects of co-transfection with BCR-ABL siRNA and GFI1B siRNA in primary CML cells In order to verify the above-described antileukemic effects, we assessed BCR-ABL siRNA and GFI1B siRNA transfection in primary cells obtained from four patients with BC of CML (patients with Y253F; F317L; and E255K mutation, and one patient with TKI resistant CML). Login to comment