PMID: 23759256

Gao L, Yang Y, Song S, Hong H, Zhao X, Li D
The association between genetic variant of MDR1 gene and breast cancer risk factors in Chinese women.
Int Immunopharmacol. 2013 Sep;17(1):88-91. doi: 10.1016/j.intimp.2013.05.025. Epub 2013 Jun 10., [PubMed]
Sentences
No. Mutations Sentence Comment
51 ABCB1 p.Arg489Cys
X
ABCB1 p.Arg489Cys 23759256:51:332
status: NEW
view ABCB1 p.Arg489Cys details
 According to the DNA, mRNA, protein reference sequences of MDR1 gene (GenBank IDs: NG_011513.1, NM_000927.4 and NP_000918.2), the sequence analysis indicated that the c.1465C>T polymorphism was a nonsynonymous mutation, which was caused by C to T mutations and resulted in arginine (Arg) to cysteine (Cys) amino acid replacement (p.Arg489Cys). Login to comment