PMID: 23612916

Prajapati R, Singh U, Patil A, Khomane KS, Bagul P, Bansal AK, Sangamwar AT
In silico model for P-glycoprotein substrate prediction: insights from molecular dynamics and in vitro studies.
J Comput Aided Mol Des. 2013 Apr;27(4):347-63. doi: 10.1007/s10822-013-9650-x. Epub 2013 Apr 24., [PubMed]
Sentences
No. Mutations Sentence Comment
197 ABCB1 p.Thr627Glu
X
ABCB1 p.Thr627Glu 23612916:197:96
status: NEW
view ABCB1 p.Thr627Glu details
ABCB1 p.Ser658Arg
X
ABCB1 p.Ser658Arg 23612916:197:119
status: NEW
view ABCB1 p.Ser658Arg details
The secondary structure prediction from HMMTOP and SAMT02 servers showed helical structure from Thr 627 to Glu 636 and Ser 658 to Arg 666 in linker region. Login to comment