PMID: 23436935

Oglesby IK, Chotirmall SH, McElvaney NG, Greene CM
Regulation of cystic fibrosis transmembrane conductance regulator by microRNA-145, -223, and -494 is altered in DeltaF508 cystic fibrosis airway epithelium.
J Immunol. 2013 Apr 1;190(7):3354-62. doi: 10.4049/jimmunol.1202960. Epub 2013 Feb 22., [PubMed]
Sentences
No. Mutations Sentence Comment
124 ABCC7 p.Gly551Asp
X
ABCC7 p.Gly551Asp 23436935:124:83
status: NEW
view ABCC7 p.Gly551Asp details
 T Positive Negative Positive 9 M DF508/DF508 Positive Positive Negative 10 M DF508/G551D Positive Positive Positive 11 F DF508/621+1G . Login to comment 125 ABCC7 p.Trp361Arg
X
ABCC7 p.Trp361Arg 23436935:125:87
status: NEW
view ABCC7 p.Trp361Arg details
 T Negative Negative Positive 12 M DF508/3007DELg Negative Negative Positive 13 F DF508/W361R Negative Positive Negative 14 F DF508/DF508 Negative Positive Negative 3356 ALTERED miRNA REGULATION OF CFTR IN CF EPITHELIUM at Central Library of the Semmelweis Univ.of Medicine on December 5, Overexpression of pre-miR-145, -223, and -494 decreases CFTR mRNA and protein expression in 16HBE14o2 cells Next, the effect of miR-145, miR-223, and miR-494 overexpression on CFTR mRNA and protein was assessed. Login to comment