PMID: 23395648

Shinde V, Marcinek P, Rani DS, Sunder SR, Arun S, Jain S, Nath I, Thangaraj K, Velavan TP, Valluri VL
Genetic evidence of TAP1 gene variant as a susceptibility factor in Indian leprosy patients.
Hum Immunol. 2013 Jun;74(6):803-7. doi: 10.1016/j.humimm.2013.01.001. Epub 2013 Feb 5., [PubMed]
Sentences
No. Mutations Sentence Comment
2 ABCB3 p.Ala565Thr
X
ABCB3 p.Ala565Thr 23395648:2:151
status: NEW
view ABCB3 p.Ala565Thr details
 The TAP1 and TAP2 genes were genotyped for four single nucleotide polymorphisms TAP1 (rs1057141 Iso333Val and rs1135216 Asp637Gly) and TAP2 (rs2228396 Ala565Thr and rs241447 Ala665Thr) by direct sequencing and ARMS-PCR. Login to comment 36 ABCB3 p.Ala565Thr
X
ABCB3 p.Ala565Thr 23395648:36:214
status: NEW
view ABCB3 p.Ala565Thr details
 Since the causative organism of both leprosy and tuberculosis represent the same genus Mycobacterium, we aim to investigate the association of TAP1 (rs1057141 Iso333Val and rs1135216 Asp637Gly) and TAP2 (rs2228396 Ala565Thr and rs241447 Ala665Thr) gene polymorphisms to the infection outcome in Indian leprosy cohort with clinically classified patient groups. Login to comment