ABCMdb

PMID: 23303252

Kakoi S, Yorimitsu T, Sato K
COPII machinery cooperates with ER-localized Hsp40 to sequester misfolded membrane proteins into ER-associated compartments.
Mol Biol Cell. 2013 Mar;24(5):633-42. doi: 10.1091/mbc.E12-08-0639. Epub 2013 Jan 9., [PubMed]

Sentences

No. Mutations Sentence Comment

108 ABCC7 p.Asp567Ala Therefore we examined the ability of the diacidic EGFP-CFTR-D567A mutant to be sequestered into ERACs, but this did not significantly affect its entry into the ERAC (Figure 5). Login to comment 113 ABCC7 p.Asp567Ala Wild-type (ANY21) cells containing the EGFP-CFTR plasmid (top) or EGFP-CFTR-D567A plasmid (bottom) were grown to mid-log phase at 23&#ba;C and incubated with copper-containing medium for 2 h to induce expression. Login to comment 186 ABCC7 p.Asp567Ala The mutation to alanine at position 567 of CFTR was introduced into the gene of EGFP-CFTR in plasmid pEGFP-CFTR using primer-directed mutagenesis, yielding pEGFP-CFTR-D567A. Login to comment