PMID: 23155000

Ahner A, Gong X, Schmidt BZ, Peters KW, Rabeh WM, Thibodeau PH, Lukacs GL, Frizzell RA
Small heat shock proteins target mutant cystic fibrosis transmembrane conductance regulator for degradation via a small ubiquitin-like modifier-dependent pathway.
Mol Biol Cell. 2013 Jan;24(2):74-84. doi: 10.1091/mbc.E12-09-0678. Epub 2012 Nov 14., [PubMed]
Sentences
No. Mutations Sentence Comment
169 ABCC7 p.Phe494Asn
X
ABCC7 p.Phe494Asn 23155000:169:68
status: NEW
view ABCC7 p.Phe494Asn details
 Purified NBD1 proteins containing a single suppressor mutation (1S, F494N) were incubated with or without purified components for 1 h at 27&#b0;C as illustrated and described in Materials and Methods. Login to comment 286 ABCC7 p.Phe494Asn
X
ABCC7 p.Phe494Asn 23155000:286:87
status: NEW
view ABCC7 p.Phe494Asn details
 For cycloheximide chases, the culture medium was changed to one containing mutation, F494N, as previously described (Rabeh et al., 2012). Login to comment