PMID: 23115232

Valentine CD, Lukacs GL, Verkman AS, Haggie PM
Reduced PDZ interactions of rescued DeltaF508CFTR increases its cell surface mobility.
J Biol Chem. 2012 Dec 21;287(52):43630-8. doi: 10.1074/jbc.M112.421172. Epub 2012 Oct 31., [PubMed]
Sentences
No. Mutations Sentence Comment
224 ABCC7 p.Ser13Phe
X
ABCC7 p.Ser13Phe 23115232:224:47
status: NEW
view ABCC7 p.Ser13Phe details
 For CFTR, Thelin et al. (41) reported that the S13F mutation increased CFTR diffusion coefficient by only b03;20%, but increased internalization by b03;2-fold. Login to comment