PMID: 23093687

Bourron O, Chebbi F, Halbron M, Saint-Martin C, Bellanne-Chantelot C, Abed A, Charbit B, Magnan C, Lacorte JM, Hartemann A
Incretin effect of glucagon-like peptide 1 receptor agonist is preserved in presence of ABCC8/SUR1 mutation in beta-cell.
Diabetes Care. 2012 Nov;35(11):e76. doi: 10.2337/dc12-0535., [PubMed]
Sentences
No. Mutations Sentence Comment
4 ABCC8 p.Cys435Arg
X
ABCC8 p.Cys435Arg 23093687:4:328
status: NEW
view ABCC8 p.Cys435Arg details
 Three informed patients were included after approbation by the local ethics committee.Patient1(38yearsold,BMI21kg/m2 , 6.2% HbA1c) and 2 (64 years old, BMI 27 kg/m2 , 7.4% HbA1c) were diagnosed at ages 15 and 17 years as having type 1 diabetes and treated with insulin for years, until ABCC8 heterozygous mutation (c.1303T.C [p.Cys435Arg] and c.4139G. Login to comment