PMID: 23055522

Ma L, Dong F, Zaid M, Kumar A, Zha X
ABCA1 protein enhances Toll-like receptor 4 (TLR4)-stimulated interleukin-10 (IL-10) secretion through protein kinase A (PKA) activation.
J Biol Chem. 2012 Nov 23;287(48):40502-12. doi: 10.1074/jbc.M112.413245. Epub 2012 Oct 10., [PubMed]
Sentences
No. Mutations Sentence Comment
106 ABCA1 p.Ala937Val
X
ABCA1 p.Ala937Val 23055522:106:30
status: NEW
view ABCA1 p.Ala937Val details
 A nonfunctional ABCA1 mutant, A937V, failed to increase p-CREB despite being expressed at a similar level as WT ABCA1 (Fig. 2A) with correct targeting to the plasma membrane (21). Login to comment