PMID: 22911334

Cerhan JR, Fredericksen ZS, Novak AJ, Ansell SM, Kay NE, Liebow M, Dogan A, Cunningham JM, Wang AH, Witzig TE, Habermann TM, Asmann YW, Slager SL
A two-stage evaluation of genetic variation in immune and inflammation genes with risk of non-hodgkin lymphoma identifies new susceptibility locus in 6p21.3 region.
Cancer Epidemiol Biomarkers Prev. 2012 Oct;21(10):1799-806. doi: 10.1158/1055-9965.EPI-12-0696. Epub 2012 Aug 21., [PubMed]
Sentences
No. Mutations Sentence Comment
4 ABCB3 p.Thr655Ala
X
ABCB3 p.Thr655Ala 22911334:4:103
status: NEW
view ABCB3 p.Thr655Ala details
ABCB3 p.Thr655Ala
X
ABCB3 p.Thr655Ala 22911334:4:104
status: NEW
view ABCB3 p.Thr655Ala details
Results: In the pooled analysis, only the TAP2 coding SNP rs241447 (minor allele frequency ¼ 0.26; Thr655Ala) at 6p21.3 (OR ¼ 1.34, 95% CI 1.17-1.53) achieved statistical significance after accounting for multiple testing (P ¼ 3.1 Â 10À5 ). Login to comment