PMID: 22889557

Visentin S, Ermondi G, Medana C, Pedemonte N, Galietta L, Caron G
Ligand-based design, in silico ADME-Tox filtering, synthesis and biological evaluation to discover new soluble 1,4-DHP-based CFTR activators.
Eur J Med Chem. 2012 Sep;55:188-94. doi: 10.1016/j.ejmech.2012.07.017. Epub 2012 Jul 23., [PubMed]
Sentences
No. Mutations Sentence Comment
10 ABCC7 p.Gly551Asp
X
ABCC7 p.Gly551Asp 22889557:10:33
status: NEW
view ABCC7 p.Gly551Asp details
ABCC7 p.Gly1349Asp
X
ABCC7 p.Gly1349Asp 22889557:10:43
status: NEW
view ABCC7 p.Gly1349Asp details
 Instead, other mutations such as G551D and G1349D cause only a gating defect. Login to comment