ABCMdb

PMID: 22796246

Kim IW, Yun HY, Choi B, Han N, Park SY, Lee ES, Oh JM
ABCB1 C3435T genetic polymorphism on population pharmacokinetics of methotrexate after hematopoietic stem cell transplantation in Korean patients: a prospective analysis.
Clin Ther. 2012 Aug;34(8):1816-26. Epub 2012 Jul 13., [PubMed]

Sentences

No. Mutations Sentence Comment

125 ABCB1 p.Gly1249Ala Minor Allele Frequency P* ABCB1 G2677T/A rs2032582 0.488 0.293 ABCB1 C3435T rs1045642 0.615 0.575 ABCC2 C-24T rs717620 0.439 0.909 ABCC2 G1249A rs2273697 0.139 0.717 ATIC C347G rs2372536 0.349 0.987 GGH C-401T rs3758149 0.375 0.371 MTHFR C677T rs1801133 0.495 0.964 MTHFR A1298C rs1801131 0.180 0.619 TYMS TSER 2R/3R rs699517 0.399 0.585 *Derived from ই2 test (Hardy-Weinberg equilibrium). Login to comment 128 ABCB1 p.Gly1249Ala Minor Allele Frequency P* ABCB1 G2677T/A rs2032582 0.488 0.293 ABCB1 C3435T rs1045642 0.615 0.575 ABCC2 C-24T rs717620 0.439 0.909 ABCC2 G1249A rs2273697 0.139 0.717 ATIC C347G rs2372536 0.349 0.987 GGH C-401T rs3758149 0.375 0.371 MTHFR C677T rs1801133 0.495 0.964 MTHFR A1298C rs1801131 0.180 0.619 TYMS TSER 2R/3R rs699517 0.399 0.585 *Derived from ␹2 test (Hardy-Weinberg equilibrium). Login to comment