PMID: 22705826

Rustemoglu A, Gul U, Gumus-Akay G, Gonul M, Yigit S, Bozkurt N, Karadag A, Piskin E, Sunguroglu A, Kadikiran A
MDR1 gene polymorphisms may be associated with Behcet's disease and its colchicum treatment response.
Gene. 2012 Sep 1;505(2):333-9. doi: 10.1016/j.gene.2012.05.040. Epub 2012 Jun 15., [PubMed]
Sentences
No. Mutations Sentence Comment
103 ABCB1 p.Ser893Ala
X
ABCB1 p.Ser893Ala 22705826:103:270
status: NEW
view ABCB1 p.Ser893Ala details
 Position Exon Amino acid change Allele BD (N=210) Control (N=260) P Genotype BD (105) Control (130) n F n F N p for HWE N p for HWE 1236 (rs1128503) 12 G412G C 109 0.524 121 0.465 0.3964 CC 33 0.0771 27 0.7270 CT 43 67 T 101 0.476 139 0.535 TT 29 36 2677 (rs2032582) 21 S893A/T G 104 0.495 124 0.477 0.5676 GG 26 0.9214 29 0.7323 GT 45 61 T 94 0.448 123 0.473 TT 22 27 A 12 0.057 13 0.050 TA 5 8 GA 7 5 3435 (rs1045642) 26 I1145I C 103 0.490 124 0.477 0.8739 CC 26 0.8449 33 0.2232 CT 51 58 T 107 0.510 136 0.523 TT 28 39 BD-Behcet's disease; n-number of alleles; N-number of subjects; F-frequency of alleles; HWE-Hardy-Weinberg equilibrium. Login to comment 104 ABCB1 p.Ser893Ala
X
ABCB1 p.Ser893Ala 22705826:104:270
status: NEW
view ABCB1 p.Ser893Ala details
 Position Exon Amino acid change Allele BD (N=210) Control (N=260) P Genotype BD (105) Control (130) n F n F N p for HWE N p for HWE 1236 (rs1128503) 12 G412G C 109 0.524 121 0.465 0.3964 CC 33 0.0771 27 0.7270 CT 43 67 T 101 0.476 139 0.535 TT 29 36 2677 (rs2032582) 21 S893A/T G 104 0.495 124 0.477 0.5676 GG 26 0.9214 29 0.7323 GT 45 61 T 94 0.448 123 0.473 TT 22 27 A 12 0.057 13 0.050 TA 5 8 GA 7 5 3435 (rs1045642) 26 I1145I C 103 0.490 124 0.477 0.8739 CC 26 0.8449 33 0.2232 CT 51 58 T 107 0.510 136 0.523 TT 28 39 BD-Behcet's disease; n-number of alleles; N-number of subjects; F-frequency of alleles; HWE-Hardy-Weinberg equilibrium. Login to comment