ABCMdb

PMID: 22655043

Kiss K, Brozik A, Kucsma N, Toth A, Gera M, Berry L, Vallentin A, Vial H, Vidal M, Szakacs G
Shifting the paradigm: the putative mitochondrial protein ABCB6 resides in the lysosomes of cells and in the plasma membrane of erythrocytes.
PLoS One. 2012;7(5):e37378. Epub 2012 May 24., [PubMed]

Sentences

No. Mutations Sentence Comment

213 ABCB6 p.Lys629Met DNA Constructs cDNA encoding wild-type human ABCB6 (NM_005689) bearing an HA-tag at its C-terminus [17] was mutated by mutagenic PCR to generate a variant harboring mutation of a universally conserved lysine residue in the Walker A sequence (K629M). Login to comment 215 ABCB6 p.Lys629Met An untagged form of both the wild-type and the non-functional mutant variant of ABCB6 (K629M, ABCB6-KM) were cloned into pSEW lentiviral vectors. Login to comment