PMID: 22271308

Portincasa P, Wang DQ
Intestinal absorption, hepatic synthesis, and biliary secretion of cholesterol: where are we for cholesterol gallstone formation?
Hepatology. 2012 May;55(5):1313-6. doi: 10.1002/hep.25604. Epub 2012 Apr 4., [PubMed]
Sentences
No. Mutations Sentence Comment
32 ABCG8 p.Asp19His
X
ABCG8 p.Asp19His 22271308:32:12
status: NEW
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ABCG8 p.Thr400Lys
X
ABCG8 p.Thr400Lys 22271308:32:23
status: NEW
view ABCG8 p.Thr400Lys details
 The ABCG8 p.D19H and p.T400K coding variants might play a role as putative susceptibility variants for gallstone formation in humans.14-16 Despite much evidence in this respect, the authors could not confirm such an interesting hypothesis, possibly due to the small cohort size. Login to comment 93 ABCG8 p.Asp19His
X
ABCG8 p.Asp19His 22271308:93:188
status: NEW
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 J Biol Chem 2004;279:33586-33592. 14. Katsika D, Magnusson P, Krawczyk M, Grunhage F, Lichtenstein P, Einarsson C, et al. Gallstone disease in Swedish twins: risk is associated with ABCG8 D19H genotype. Login to comment