PMID: 21873242

Aung T, Chapuy B, Vogel D, Wenzel D, Oppermann M, Lahmann M, Weinhage T, Menck K, Hupfeld T, Koch R, Trumper L, Wulf GG
Exosomal evasion of humoral immunotherapy in aggressive B-cell lymphoma modulated by ATP-binding cassette transporter A3.
Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15336-41. Epub 2011 Aug 25., [PubMed]
Sentences
No. Mutations Sentence Comment
92 ABCA3 p.Asn568Asp
X
ABCA3 p.Asn568Asp 21873242:92:92
status: NEW
view ABCA3 p.Asn568Asp details
As a control, enforced expression of a nonfunctional ABCA3 mutated in the ATP-binding site (N568D) was not sufficient to induce such effects (Fig. 6 D-F) (16). Login to comment
96 ABCA3 p.Asn568Asp
X
ABCA3 p.Asn568Asp 21873242:96:92
status: NEW
view ABCA3 p.Asn568Asp details
As a control, enforced expression of a nonfunctional ABCA3 mutated in the ATP-binding site (N568D) was not sufficient to induce such effects (Fig. 6 D-F) (16). Login to comment
159 ABCA3 p.Asn568Asp
X
ABCA3 p.Asn568Asp 21873242:159:232
status: NEW
view ABCA3 p.Asn568Asp details
To analyze ABCA3 function in exosome release, both silencing of ABCA3 with two independent shABCA3 constructs (PLKO.1-shRNA.38 and .39) and enforced gene expression with an ABCA3 wild-type plasmid and a nonfunctional mutant (pABCA3 N568D) were applied. Login to comment
163 ABCA3 p.Asn568Asp
X
ABCA3 p.Asn568Asp 21873242:163:232
status: NEW
view ABCA3 p.Asn568Asp details
To analyze ABCA3 function in exosome release, both silencing of ABCA3 with two independent shABCA3 constructs (PLKO.1-shRNA.38 and .39) and enforced gene expression with an ABCA3 wild-type plasmid and a nonfunctional mutant (pABCA3 N568D) were applied. Login to comment