PMID: 21706123

Narita S, Tsuchiya N, Yuasa T, Maita S, Obara T, Numakura K, Tsuruta H, Saito M, Inoue T, Horikawa Y, Satoh S, Habuchi T
Outcome, clinical prognostic factors and genetic predictors of adverse reactions of intermittent combination chemotherapy with docetaxel, estramustine phosphate and carboplatin for castration-resistant prostate cancer.
Int J Clin Oncol. 2012 Jun;17(3):204-11. Epub 2011 Jun 25., [PubMed]
Sentences
No. Mutations Sentence Comment
90 ABCG2 p.Val12Met
X
ABCG2 p.Val12Met 21706123:90:193
status: NEW
view ABCG2 p.Val12Met details
 Primers Restriction enzyme Forward Reverse MAP4 Intron rs56313601 TGCATGGTTTCCTTTCCCCTA TCTCTGAAACGTGTGTGGCTT BccI MAPT Intron rs3744460 AAAGTGGAGGCGTCCTTGCGA CAGCTTCTTATTAATTATCTGC MnlI ABCG2 V12M rs2231137 GCTTTTCTGTCTGCAGAAAGAT GAAGCTGTCGCGGGGAAGCC TspRI CYP3A5 A6986G rs776746 ATGGAGAGTGGCATAGGAGATA TGTGGTCCAAACAGGGAAGAAATA SspI XRCC1 C194T rs1799782 ATGCTTGGCCAGTTCCGTGTGAAG CACCTGGGGATGTCTTGTTGATCC AluI XRCC1 A399G rs25487 TCCTCCACCTTGTGCTTTCT AGTAGTCTGCTGGCTCTGGG NciI ABCB1 C3435T rs1045642 TTGATGGCAAAGAAATAAAGC CTTACATTAGGCAGTGACTCG MboI ABCB1 Intron rs7779562 TGTTCTGCAATGAGAAGAATAA ATTGTAACACAAATTAATTATC TaqI Genetic variation affecting adverse reaction Next, we explored the association between each genotype and severe leukocytopenia. Login to comment