PMID: 21148790

Tamanini A, Borgatti M, Finotti A, Piccagli L, Bezzerri V, Favia M, Guerra L, Lampronti I, Bianchi N, Dall'Acqua F, Vedaldi D, Salvador A, Fabbri E, Mancini I, Nicolis E, Casavola V, Cabrini G, Gambari R
Trimethylangelicin reduces IL-8 transcription and potentiates CFTR function.
Am J Physiol Lung Cell Mol Physiol. 2011 Mar;300(3):L380-90. Epub 2010 Dec 10., [PubMed]
Sentences
No. Mutations Sentence Comment
39 ABCC7 p.Trp1282*
X
ABCC7 p.Trp1282* 21148790:39:54
status: NEW
view ABCC7 p.Trp1282* details
IB3-1 cells, derived from a CF patient with a F508del/W1282X mutant genotype, were grown as previously described (3, 8, 15, 16, 32); non-CF Calu-3, a cell line obtained from a human lung adenocarcinoma derived from submucosal gland of proximal bronchial airways, and CF CuFi-1 cell line, obtained from human bronchial epithelium derived from a CF patient with a F508del/ F508del mutant genotype, were cultured on Transwell membranes (41). Login to comment
42 ABCC7 p.Trp1282*
X
ABCC7 p.Trp1282* 21148790:42:54
status: NEW
view ABCC7 p.Trp1282* details
IB3-1 cells, derived from a CF patient with a F508del/W1282X mutant genotype, were grown as previously described (3, 8, 15, 16, 32); non-CF Calu-3, a cell line obtained from a human lung adenocarcinoma derived from submucosal gland of proximal bronchial airways, and CF CuFi-1 cell line, obtained from human bronchial epithelium derived from a CF patient with a F508del/ F508del mutant genotype, were cultured on Transwell membranes (41). Login to comment