PMID: 21070853

Huwait EA, Greenow KR, Singh NN, Ramji DP
A novel role for c-Jun N-terminal kinase and phosphoinositide 3-kinase in the liver X receptor-mediated induction of macrophage gene expression.
Cell Signal. 2011 Mar;23(3):542-9. Epub 2010 Nov 8., [PubMed]
Sentences
No. Mutations Sentence Comment
141 ABCA1 p.Ser198Ala
X
ABCA1 p.Ser198Ala 21070853:141:134
status: NEW
view ABCA1 p.Ser198Ala details
The action of this phosphorylation was gene-specific as the expression of only some LXR targets was increased in cells expressing the S198A phosphorylation-deficient mutant compared to those for the wild-type receptor [27]. Login to comment
142 ABCA1 p.Ser198Ala
X
ABCA1 p.Ser198Ala 21070853:142:134
status: NEW
view ABCA1 p.Ser198Ala details
The action of this phosphorylation was gene-specific as the expression of only some LXR targets was increased in cells expressing the S198A phosphorylation-deficient mutant compared to those for the wild-type receptor [27]. Login to comment