PMID: 20858845

Ikebuchi Y, Ito K, Takada T, Anzai N, Kanai Y, Suzuki H
Receptor for activated C-kinase 1 regulates the cell surface expression and function of ATP binding cassette G2.
Drug Metab Dispos. 2010 Dec;38(12):2320-8. Epub 2010 Sep 21., [PubMed]
Sentences
No. Mutations Sentence Comment
279 ABCG2 p.Cys608Gly
X
ABCG2 p.Cys608Gly 20858845:279:66
status: VERIFIED
view ABCG2 p.Cys608Gly details
ABCG2 p.Cys592Gly
X
ABCG2 p.Cys592Gly 20858845:279:60
status: VERIFIED
view ABCG2 p.Cys592Gly details
 Another study showed that the expression level of the ABCG2 C592G/C608G mutant, which lacks the intramolecular disulfide bond, was increased by MG132 treatment, whereas that of the wild type was not affected (Wakabayashi et al., 2007). Login to comment