PMID: 20561529

Aleksandrov AA, Kota P, Aleksandrov LA, He L, Jensen T, Cui L, Gentzsch M, Dokholyan NV, Riordan JR
Regulatory insertion removal restores maturation, stability and function of DeltaF508 CFTR.
J Mol Biol. 2010 Aug 13;401(2):194-210. Epub 2010 Jun 16., 2010-08-13 [PubMed]
Sentences
No. Mutations Sentence Comment
154 ABCC7 p.Val510Cys
X
ABCC7 p.Val510Cys 20561529:154:143
status: NEW
view ABCC7 p.Val510Cys details
ABCC7 p.Val510Cys
X
ABCC7 p.Val510Cys 20561529:154:144
status: NEW
view ABCC7 p.Val510Cys details
ABCC7 p.Gly1069Cys
X
ABCC7 p.Gly1069Cys 20561529:154:149
status: NEW
view ABCC7 p.Gly1069Cys details
ABCC7 p.Gly1069Cys
X
ABCC7 p.Gly1069Cys 20561529:154:150
status: NEW
view ABCC7 p.Gly1069Cys details
ABCC7 p.Gln1280Cys
X
ABCC7 p.Gln1280Cys 20561529:154:122
status: NEW
view ABCC7 p.Gln1280Cys details
 HEK 293 cells were transiently transfected with Cys-less ΔF508 CFTR with Cys pairs introduced at the CL2-NBD2 (C276-Q1280C) or CL4-NBD1 (V510C-G1069C) interfaces in the absence or presence of ΔRI. Login to comment