PMID: 20351751

Laechelt S, Turrini E, Ruehmkorf A, Siegmund W, Cascorbi I, Haenisch S
Impact of ABCC2 haplotypes on transcriptional and posttranscriptional gene regulation and function.
Pharmacogenomics J. 2011 Feb;11(1):25-34. Epub 2010 Mar 30., [PubMed]
Sentences
No. Mutations Sentence Comment
30 ABCC2 p.Val417Ile
X
ABCC2 p.Val417Ile 20351751:30:247
status: NEW
view ABCC2 p.Val417Ile details
 Genotyping After isolation of DNA according to manufacture`s instruction (DNeasy Tissue kit, Qiagen, Hilden, Germany) SK-Hep 1, A-498 and Caco-2 cells were genotyped for the polymorphisms À24C4T (rs717620), À23G4A (rs17216156), 1249G4A (V417I, rs2273697) and 3972C4T (I1324I, rs3740066) by pyrosequencing (PSQ) using the PSQ96HS system (Biotage, Uppsala, Sweden) following a standard protocol as described before.9 Primers were created by the Assay Design software version 1.0 (Biotage). Login to comment