PMID: 20309575

Gouyer V, Leir SH, Tetaert D, Liu Y, Gottrand F, Harris A, Desseyn JL
The characterization of the first anti-mouse Muc6 antibody shows an increased expression of the mucin in pancreatic tissue of Cftr-knockout mice.
Histochem Cell Biol. 2010 May;133(5):517-25. Epub 2010 Mar 23., [PubMed]
Sentences
No. Mutations Sentence Comment
37 ABCC7 p.Ser489*
X
ABCC7 p.Ser489* 20309575:37:67
status: NEW
view ABCC7 p.Ser489* details
Cftr-knockout (Cftr¡/¡) mice used are homozygous for the S489X-CFTR mutation (B6;129-Cftrtm1Unc ) (Snouwaert et al. 1992). Login to comment
38 ABCC7 p.Ser489*
X
ABCC7 p.Ser489* 20309575:38:4
status: NEW
view ABCC7 p.Ser489* details
The S489X mouse third generation backcross to C57BL/6 are maintained at the French Centre of Transgenesis, Archiving and Animal Models in Orleans (MF Bertrand, CDTA, Orléans, France) by random mating of heterozygous mice and are provided with their wild-type littermates (Cftr+/+) at 21-25 days of age. Login to comment