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PMID: 20138281
Fitzgerald ML, Mujawar Z, Tamehiro N
ABC transporters, atherosclerosis and inflammation.
Atherosclerosis. 2010 Aug;211(2):361-70. Epub 2010 Jan 21.,
[PubMed]
Sentences
No.
Mutations
Sentence
Comment
1587
ABCA1 p.Trp590Ser
X
ABCA1 p.Trp590Ser 20138281:1587:61
status:
NEW
view ABCA1 p.Trp590Ser details
The exception to this behavior is the activity of the ABCA1 (
W590S
) missense mutant that is still able to bind and release apoA-I back into the media but fails to transfer lipid to the released apoA-I [24,25,28,29].
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