PMID: 20089831

Koulov AV, Lapointe P, Lu B, Razvi A, Coppinger J, Dong MQ, Matteson J, Laister R, Arrowsmith C, Yates JR 3rd, Balch WE
Biological and structural basis for Aha1 regulation of Hsp90 ATPase activity in maintaining proteostasis in the human disease cystic fibrosis.
Mol Biol Cell. 2010 Mar 15;21(6):871-84. Epub 2010 Jan 20., 2010-03-15 [PubMed]
Sentences
No. Mutations Sentence Comment
283 ABCC7 p.Glu267Lys
X
ABCC7 p.Glu267Lys 20089831:283:38
status: NEW
view ABCC7 p.Glu267Lys details
 Notably, these included C207S, E221A, E267K, D293A, E297A, T298A, and E313A, residues that may contribute to the stability of the Aha1 interaction with Hsp90 (Figures 3 and 4B). Login to comment