PMID: 19852935

Gehring EM, Lam RS, Siraskar G, Koutsouki E, Seebohm G, Ureche ON, Ureche L, Baltaev R, Tavare JM, Lang F
PIKfyve upregulates CFTR activity.
Biochem Biophys Res Commun. 2009 Dec 18;390(3):952-7. Epub 2009 Oct 21., 2009-12-18 [PubMed]
Sentences
No. Mutations Sentence Comment
141 ABCC7 p.Ser422Asp
X
ABCC7 p.Ser422Asp 19852935:141:152
status: NEW
view ABCC7 p.Ser422Asp details
 water CFTR CFTR PIKfyve CFTR S318APIKfyve ΔF508CFTR PIKfyve C FTR +H 2 O C FTR +H 2 O C FTR +PIKfyve C FTR + S318A PIKfyve C FTR +PIKfyve C FTR + S422D SG K1 ~170 KDa ~170 KDa A B Fig. 4. Login to comment