PMID: 19620404

Cormet-Boyaka E, Hong JS, Berdiev BK, Fortenberry JA, Rennolds J, Clancy JP, Benos DJ, Boyaka PN, Sorscher EJ
A truncated CFTR protein rescues endogenous DeltaF508-CFTR and corrects chloride transport in mice.
FASEB J. 2009 Nov;23(11):3743-51. Epub 2009 Jul 20., [PubMed]
Sentences
No. Mutations Sentence Comment
215 ABCC7 p.His1085Arg
X
ABCC7 p.His1085Arg 19620404:215:244
status: NEW
view ABCC7 p.His1085Arg details
 As previously reported, the rescue was specific to mutations located in the amino-terminal part of CFTR (N-tail and NBD1), as the CFTR fragment 1-633 did not rescue a CFTR mutant harboring a mutation located close to the carboxyl tail of CFTR, H1085R-CFTR (14). Login to comment