PMID: 19528366

Delou JM, Lopes AG, Capella MA
Unveiling the role of multidrug resistance proteins in hypertension.
Hypertension. 2009 Aug;54(2):210-6. Epub 2009 Jun 15., [PubMed]
Sentences
No. Mutations Sentence Comment
54 ABCG2 p.Val12Met
X
ABCG2 p.Val12Met 19528366:54:250
status: NEW
view ABCG2 p.Val12Met details
 It is well established that age and hypertension are the most powerful risk factors for stroke.66,67 In a very recent cardiovascular health study, in which 74 genetic variants were tested, it was found that a single nucleotide polymorphism of ABCG2 (Val12Met) was associated with increased risk of ischemic stroke in both white and black participants.68 The authors showed that homozygotes of the Val allele of ABCG2 were at higher risk of stroke than carriers of the Met allele. Login to comment