PMID: 19475687

Halilbasic E, Fiorotto R, Fickert P, Marschall HU, Moustafa T, Spirli C, Fuchsbichler A, Gumhold J, Silbert D, Zatloukal K, Langner C, Maitra U, Denk H, Hofmann AF, Strazzabosco M, Trauner M
Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2-/- mice.
Hepatology. 2009 Jun;49(6):1972-81., [PubMed]
Sentences
No. Mutations Sentence Comment
27 ABCC7 p.Ser489*
X
ABCC7 p.Ser489* 19475687:27:53
status: NEW
view ABCC7 p.Ser489* details
 Congenic B6.129P2-Cftrtm1Unc mice, which possess the S489X mutation that blocks transcription of Cftr,13 were fed with Peptamen (Nestle Clinical Nutrition, Deerfield, IL) or with Peptamen containing norUDCA (in a dosage equivalent to that used in Mdr2-/- mice) for 1 week. Login to comment