PMID: 19470503

Wang X, Tanaka H, Baba M, Cheng YC
Retention of metabolites of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine, a novel anti-human immunodeficiency virus type 1 thymidine analog, in cells.
Antimicrob Agents Chemother. 2009 Aug;53(8):3317-24. Epub 2009 May 26., [PubMed]
Sentences
No. Mutations Sentence Comment
23 ABCC4 p.Met184Val
X
ABCC4 p.Met184Val 19470503:23:169
status: NEW
view ABCC4 p.Met184Val details
 Moreover, 4Ј-Ed4T was found to be active against multidrug-resistant HIV-1 clinical isolates, while a unique pattern of RT resistance mutations (P119S, T165A, and M184V) in the virus was observed under the selection pressure of 4Ј-Ed4T in vitro (13). Login to comment