PMID: 19019257

Gylling H, Hallikainen M, Raitakari OT, Laakso M, Vartiainen E, Salo P, Korpelainen V, Sundvall J, Miettinen TA
Long-term consumption of plant stanol and sterol esters, vascular function and genetic regulation.
Br J Nutr. 2009 Jun;101(11):1688-95. Epub 2008 Nov 19., [PubMed]
Sentences
No. Mutations Sentence Comment
155 ABCG8 p.Thr400Lys
X
ABCG8 p.Thr400Lys 19019257:155:167
status: NEW
view ABCG8 p.Thr400Lys details
 The present results differ from a previous study conducted in healthy subjects, in whom the serum plant sterol response to stanol esters was associated with the ABCG8 T400K genotype(23) . Login to comment 176 ABCG8 p.Thr400Lys
X
ABCG8 p.Thr400Lys 19019257:176:28
status: NEW
view ABCG8 p.Thr400Lys details
 During the intervention the T400K polymorphic site of ABCG8 was associated with the increase in IMT. Login to comment 179 ABCG8 p.Thr400Lys
X
ABCG8 p.Thr400Lys 19019257:179:27
status: NEW
view ABCG8 p.Thr400Lys details
 Since at baseline the same T400K polymorphic site of ABCG8 separated subjects with a profile of cholesterol metabolism characteristic for the metabolic syndrome, we assume that low cholesterol absorption and high synthesis as part of the metabolic syndrome is unfavourable for the progression of IMT. Login to comment