ABCMdb

PMID: 18941142

Nandi S, Ma L, Denis M, Karwatsky J, Li Z, Jiang XC, Zha X
ABCA1-mediated cholesterol efflux generates microparticles in addition to HDL through processes governed by membrane rigidity.
J Lipid Res. 2009 Mar;50(3):456-66. Epub 2008 Oct 21., [PubMed]

Sentences

No. Mutations Sentence Comment

5 ABCA1 p.Ala937Val For instance, a nucleotide binding domain mutation in ABCA1 (A937V) that impaired HDL generation also abolished microparticle release. Login to comment 151 ABCA1 p.Ala937Val A: 3 H-cholesterol labeled BHK-mock, ABCA1, ABCA1-A937V cells were induced for 20 h and incubated with DMEM without apoA-I for 4 h. B: 3 H-cholesterol labeled BHK-mock and ABCA1 were induced and incubated with DMEM with or without 50 mM PKI. Login to comment